KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RET
All Species:
9.09
Human Site:
Y952
Identified Species:
18.18
UniProt:
P07949
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07949
NP_065681.1
1114
124319
Y952
V
T
L
G
G
N
P
Y
P
G
I
P
P
E
R
Chimpanzee
Pan troglodytes
XP_001171246
813
90715
A659
R
L
P
V
K
W
M
A
P
E
A
L
F
D
R
Rhesus Macaque
Macaca mulatta
XP_001090823
731
81824
A577
R
L
P
V
K
W
M
A
P
E
A
L
F
D
R
Dog
Lupus familis
XP_543915
1108
124018
Y946
V
T
L
G
G
N
P
Y
P
G
I
P
P
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P35546
1115
123855
Y953
V
T
L
G
G
N
P
Y
P
G
I
P
P
E
R
Rat
Rattus norvegicus
Q04589
822
91806
A668
R
L
P
V
K
W
M
A
P
E
A
L
F
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507715
665
75620
L511
P
G
I
A
P
E
R
L
F
N
L
L
K
T
G
Chicken
Gallus gallus
P18461
823
92281
V669
T
T
N
G
R
L
P
V
K
W
M
A
P
E
A
Frog
Xenopus laevis
Q03364
813
91322
W659
N
G
R
L
P
V
K
W
M
A
P
E
A
L
F
Zebra Danio
Brachydanio rerio
Q8JG38
817
91370
V663
T
T
N
G
R
L
P
V
K
W
M
A
P
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
N898
D
T
E
Y
Y
R
K
N
T
N
G
R
L
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26614
972
110463
G818
F
Y
R
K
T
T
D
G
R
L
P
V
K
W
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.4
27.9
86.4
N.A.
83.4
28.9
N.A.
43
27.5
28.1
27.7
N.A.
23.6
N.A.
N.A.
24
Protein Similarity:
100
42.2
41.5
92
N.A.
90.2
43
N.A.
50.5
43.5
42.3
42
N.A.
37.7
N.A.
N.A.
41.2
P-Site Identity:
100
13.3
13.3
100
N.A.
100
13.3
N.A.
0
33.3
0
33.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
20
20
100
N.A.
100
20
N.A.
13.3
40
6.6
40
N.A.
6.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
25
0
9
25
17
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
0
0
0
0
0
25
0
% D
% Glu:
0
0
9
0
0
9
0
0
0
25
0
9
0
42
0
% E
% Phe:
9
0
0
0
0
0
0
0
9
0
0
0
25
0
9
% F
% Gly:
0
17
0
42
25
0
0
9
0
25
9
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
25
0
0
0
9
% I
% Lys:
0
0
0
9
25
0
17
0
17
0
0
0
17
0
0
% K
% Leu:
0
25
25
9
0
17
0
9
0
9
9
34
9
9
0
% L
% Met:
0
0
0
0
0
0
25
0
9
0
17
0
0
0
9
% M
% Asn:
9
0
17
0
0
25
0
9
0
17
0
0
0
0
0
% N
% Pro:
9
0
25
0
17
0
42
0
50
0
17
25
42
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
25
0
17
0
17
9
9
0
9
0
0
9
0
0
50
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
17
50
0
0
9
9
0
0
9
0
0
0
0
9
0
% T
% Val:
25
0
0
25
0
9
0
17
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
25
0
9
0
17
0
0
0
9
0
% W
% Tyr:
0
9
0
9
9
0
0
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _